1. Tardigrade
  2. Question
  3. Biology
  4. Choose the correct option w.r.t. sickle cell anaemia a. Substitution of amino acid in the globin protein results due to single base substitution at the sixth codon of the beta globin gene from GAG to GUG b. Heterozygous individuals exhibit sickle-cell trait. c. HbA peptide has amino acid sequence as Val-His-Leu-Thr-Pro-Val. d. Mutant haemoglobin molecule shows polymerisation under low oxygen tension.

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Q. Choose the correct option w.r.t. sickle cell anaemia
a. Substitution of amino acid in the globin protein results due to single base substitution at the sixth codon of the beta globin gene from GAG to GUG
b. Heterozygous individuals exhibit sickle-cell trait.
c. HbA peptide has amino acid sequence as Val-His-Leu-Thr-Pro-Val.
d. Mutant haemoglobin molecule shows polymerisation under low oxygen tension.

Molecular Basis of Inheritance

Solution:

Correct answer is (d) a, b, d