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  4. Change of pH may disturb protein structure and thus affecting its functions. Which level of protein structure is not generally affected by the change in pH ?

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Q. Change of $pH$ may disturb protein structure and thus affecting its functions. Which level of protein structure is not generally affected by the change in $pH$ ?

NTA AbhyasNTA Abhyas 2020

Solution:

The primary structure of protein has peptide bonds only that are resistant to the change in $pH$ . In contrast, secondary and tertiary structure of proteins have covalent bonds, hydrogen bonds that can be easily affected by the change in $pH$ • The primary structure of a protein — its amino acid sequence — drives the folding and intramolecular bonding of the linear amino acid chain, which ultimately determines the protein's unique three-dimensional shape.