Q. Blood cholesterol lowering agent
NTA AbhyasNTA Abhyas 2020
Solution:
Statins: These are produced by the yeast- Monascus purpureus. Statins have been commercialized as blood-cholesterol lowering agents. It acts competitively inhibiting the enzyme HMG CoA reductase responsible for the synthesis of cholesterol.
In competitive inhibition, inhibitors resemble to substrate and bind to the active site of the enzyme and inhibits enzyme activity. This inhibition is overcome by increasing the amount of substrate concentration.
In competitive inhibition, inhibitors resemble to substrate and bind to the active site of the enzyme and inhibits enzyme activity. This inhibition is overcome by increasing the amount of substrate concentration.