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  4. Assertion: Solubility of proteins is minimum at the isoelectric point. Reason: At isoelectric point, protein molecule behaves as a zwitter ion.

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Q. Assertion : Solubility of proteins is minimum at the isoelectric point.
Reason : At isoelectric point, protein molecule behaves as a zwitter ion.

AIIMSAIIMS 2015Biomolecules

Solution:

At isoelectric point, protein molecules behave as zwitter ions and hence, do not move toward any electrode or act as neutral molecules. This reduces their solubility to minimum and thus, helps in their separation and purification.