Question

Arrange these events in a sequence in the cell cycle:
A. Synthesis of deoxyribonucleotides
B. Synthesis of tubulin protein
C. Synthesis of histone protein

• A. A — C — B
• B. A — B — C
• C. B — A — C
• D. C— A — B

Answer 1

Answer: (A)

Cell Cycle comprises of mainly two phases.-Interphase and M-phase.
Interphase - Most active phase of the cell cycle, In the interphase cell, is preparing for division by undergoing both cell growth and DNA replication in an orderly manner. Howard and Pele classified interphase in G1, S, G2 phase.
DNA is made during the S phase of the cell cycle, and the free deoxyribonucleotides are made at this time. These deoxyribonucleotides serve as precursors of DNA, which further helps in DNA replication.
Histones are basic and positively charged proteins, due to which they easily associate with the negatively charged DNA. During Cell Cycle, in the synthetic(S) phase of interphase, replication of DNA and synthesis of histone proteins occur. Histone proteins are very important for the packaging of a long polynucleotide chain of DNA.
G2 phase which occurs just after DNA replication(S phase) is a period of protein synthesis and rapid cell growth to prepare the cell for mitosis. During this phase, microtubules reorganize to form a spindle apparatus (preprophase).