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Q. Arrange priority of $CIP$ sequence of given groups in decreasing order-
(I) $OH$
(II) $COOH$
(III) $CHOHCH_{3}$
(IV) $CH_{2}OH$

NTA AbhyasNTA Abhyas 2022

Solution:

According to Cahn-Ingold-Prelong $\left(C I P\right)$ sequence, priority order of groups is decided by atomic number or atomic mass of Electronegativity of connecting atom $\left(o > c\right)$ conjugative atoms.
$-OH>-COOH>-CH\left(O H\right)CH_{3}>-CH_{2}OH$