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  4. Arrange priority of CIP sequence of given groups in decreasing order- (I) OH (II) COOH (III) CHOHCH3 (IV) CH2OH

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Q. Arrange priority of $CIP$ sequence of given groups in decreasing order-

(I) $OH$

(II) $COOH$

(III) $CHOHCH_{3}$

(IV) $CH_{2}OH$

NTA AbhyasNTA Abhyas 2020Organic Chemistry – Some Basic Principles and Techniques

Solution:

According to Cahn-Ingold-Prelong $\left(C I P\right)$ sequence, priority order of groups is decided by atomic number or atomic mass of conjugative atoms.

$-OH>-COOH>-CH\left(O H\right)CH_{3}>-CH_{2}OH$