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Q.
An individual affected by phenylketonuria lacks an enzyme that converts the amino acid ________ into _______.
NTA AbhyasNTA Abhyas 2022
Solution:
Phenylketonuria is an inborn error of metabolism where the individual has reduced metabolism of the amino acid phenylalanine. Mutation in the gene causes inhibition of the production of enzyme phenylalanine hydroxylase that converts phenylalanine into tyrosine. Such mutation leads to mental retardation, with reduction in hair and skin pigmentation. It is a recessive autosomal disorder.