1. Tardigrade
  2. Question
  3. Chemistry
  4. Amine that cannot be prepared by Gabriel phthalimide synthesis is

Question Error Report

Thank you for reporting, we will resolve it shortly

Back to Question

Q. Amine that cannot be prepared by Gabriel phthalimide synthesis is

Amines

Solution:

Aniline cannot be prepared by this method because aryl halides do not undergo nucleophilic substitution with potassium phthalimide under ordinary conditions to give $N$-phenyl phthalimide (i.e., cleavage of $C-X$ bond in haloarenes is quite difficult).
image