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Q. Alzheimer disease in humans is associated with the deficiency of

AIPMTAIPMT 2009Neural Control and Coordination

Solution:

Alzheimer's disease is a neurological disease characterized by progressive loss of intellectual ability. The disease, which is named after German physician Alois Alzheimer (1864-1915), is associated with general shrinkage of the brain tissue, with deposits of (3-amyloid protein and abnormal filaments composed of tau protein in the brain, and changes in the neurotransmitter systems within the brain that include a loss in the activity of cholinergic neurons (neurons releasing acetylcholine). Some inherited forms are associated with a genetic locus on chromosome 21. 18 (c) : Hypothalamus is the thermoregulatory center of the body. It keeps body temperature at 37°C by means of a complex thermostat system.