Q. A woman with two genes for haemophilia and one gene for colour blindness on one of the 'X' chromosomes marries a normal man. How will the progeny be?
AIPMTAIPMT 1998Principles of Inheritance and Variation
Solution:
Haemophilia is a defect of blood which prevents its clotting. Colour blindness is the inability of certain human beings to distinguish red from green colour. Both these diseases are produced by a recessive gene which lies on the X-chromosomes. A woman having both gene for haemophilia on one X-chromosome and gene for colourblindness on another X-chromosome will have genotype XhXc. Thus, progeny includes 50% haemophilic daughters (carrier) and 50% colour blind daughters (carrier).
