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  4. A person with blood group AB has which of the following antigens in his RBCs ?

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Q. A person with blood group AB has which of the following antigens in his RBCs ?

Odisha JEEOdisha JEE 2010Body Fluids and Circulation

Solution:

Karl Landsteiner reported first time ABO blood groups in human beings. $A , B$ and $O$ blood groups were discovered by Landsteiner (1900) while AB blood group was found out by de Castello and Steini (1902). ABO blood groups are determined by the gene $I$ (isoagglutinin). There are three alleles, $I^{ A }, I^{B}$ and $I^{O}$ of this gene. Proteins produced by the $I^{ A }$ and $I^{ B }$ alleles are called $A$ antigen and $B$ antigen. Individuals with AB blood group have both antigen $A$ and antigen $B$ on their RBCs and no antibodies for either of the antigens in their plasma.