The total number of offsprings in the F2 generation is represented by 4n, where n = 1 for monohybrid, n = 2 for dihybrid, etc. Thus the total number of offsprings in the F2 generation of tetrahybrid cross is 44 = 256. Out of these only two offsprings will resemble the parents genotypically. Thus their proportion is 2/256, which is 1/128.