1. Tardigrade
  2. Question
  3. Chemistry
  4. The total number among following ethers which cannot be prepared by Williamson's synthesis is: CH3OCH2CH3, C6H5OCH3, (C6H5)2O, (CH3)3COCH3, (C2H5)2O, (CH3)3C - O - C(CH3)3

Q. The total number among following ethers which cannot be prepared by Williamson's synthesis is:

 352  146 NTA AbhyasNTA Abhyas 2022 Report Error

Answer: 2

Solution:

In Williamson's synthesis,
i. alkyl halide and alkoxide give the best yield of corresponding ethers.
ii. In case of, alkyl halide, elimination competes over substitution and alkene is obtained as a product.
iii. Aryl halides do not undergo nucleophilic substitution unless it is activated by the presence of electron-withdrawing group.
Thus, and cannot be prepared by Williamson's synthesis.