Q. The following statements describe the process of translation.
I. An amide linkage is formed between adjacent amino acids.
II. Hydrogen bonds are formed between the anticodon and the codon.
III. mRNA binds to the ribosome.
IV. tRNA enters the ribosome carrying a specific amino acid.
In which order does this process take place?

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Solution:

Translation refers to the process of polymerization of amino acids to form a polypeptide. It occurs at ribosomes. It has three phases: initiation, elongation and termination. During initiation, mRNA combines with ribosomes. Then a tRNA carrying methionine is brought at the P site. There is a codon-anticodon pairing with the help of hydrogen bonds. Then elongation occurs, in which a new codon is exposed at A Site. A new tRNA carrying specific amino acid to that codon is brought again. There is codon-anticodon pairing and amino acid is accepted. Further, a peptide bond is formed at the P site between the first amino acid and the new amino acid brought at the A site. The ribosome moves from codon to codon along the mRNA. amino acids are added one by one, and translated into polypeptide sequences.