We first select 2 men out of 7 in 7C2 ways. Now we exclude the wives of these two selected men and so select 2 ladies from remaining 5 ladies in 5C2 ways. Let A,B be two men and X,Y be the ladies playing in one set. Then we can have
(i) A and X plying against B and Y.
(ii) A and Y playing against B and X.
Then the total number of ways is 7C2×5C2×2=21×10×2=420.