Microtubules are one of the essential protein filaments of the cytoskeletons of probably all eukaryotic cells and of their cilia, flagella, basal bodies, centrioles and mitotic and meiosis spindles. Each microtubule is made up of hollow cylinder of 13 proto fi laments of a tubulin protein. The diameter of each microfibril is 25nm. The function of microtubule is to guide organelle and chromosome movement in the cell, cause cell elongation and help in movement of cilia/flagella.