Question

Juxtaglomerular apparatus is made up of

• A. juxtaglomerular cells, macula densa and lads cells
• B. juxtaglomerular cells, Purkinje cells and chief cells
• C. juxtaglomerular cells, lads cells and myoepithelial cells
• D. juxtaglomerular cells, macula densa and argentaffin cells.

Answer 1

Answer: (A)

Juxtaglomerular cells are the smooth muscle cells of both the afferent and efferent arterioles that are swollen and contain dark granules. These cells secrete renin. Macula densa are the epithelial cells of the distal convoluted tubule that come in contact with the afferent and efferent arterioles. These cells are more dense than the other tubular cells. They act as chemoreceptors. Lads cells are located in the interval between the macula densa and the afferent and efferent arterioles. The function of lacis cells is unknown. All these cells make up juxtaglomerular apparatus.