Q.
Identify the correct order of reactivity towards electrophilic substitution reactions of the following compounds.
2158
189
Organic Chemistry – Some Basic Principles and Techniques
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Solution:
In electrophilic substitution reaction, electrophile (E+) is looking for an electron rich nucleus. +I effect of (CH3)3C—>(CH3)2CH— —Cl shows -I effect and +R (or +M) effect. —NO2 shows −I effect and −R (or -M) effect. Hence the correct order towards SE reaction is 4>1>3>2.