Assertion (A) Replication on one strand of DNA is continuous and on another it is discontinuous. Reason (R) The DNA polymerase works in 3' arrow 5' direction.

Question

Assertion (A) Replication on one strand of DNA is continuous and on another it is discontinuous. Reason (R) The DNA polymerase works in 3' arrow 5' direction. (A) If both A and R are true and R is the correct explanation of A (B) If both A and R are true, but R is not the correct explanation of A (C) If A is true, but R is false (D) If A is false, but R is true

Tardigrade Admin · Accepted Answer

Both Assertion and Reason are true and Reason is the correct explanation of Assertion.
The DNA-dependent DNA polymerase works in the

5^{'} \to 3^{'}

direction requiring a free

3^{'} - O H

of a pre-existing polynucleotide for initiating DNA replication. Thus, it continuously synthesises the strand
having polarity

3^{'} \to 5^{'}

Replication of the lagging strand

(5^{'} \to 3^{'})

generates small polynucleotide fragments, okazaki fragments. The replication of this strand is discontinuous.

Q. Assertion (A) Replication on one strand of DNA is continuous and on another it is discontinuous. Reason (R) The DNA polymerase works in 3′→5′ direction.

If both A and R are true and R is the correct explanation of A

If both A and R are true, but R is not the correct explanation of A

If A is true, but R is false

If A is false, but R is true

Q. Assertion (A) Replication on one strand of DNA is continuous and on another it is discontinuous.
Reason (R) The DNA polymerase works in $3^{'} \to 5^{'}$ direction.