Q. Assertion: A coenzymes or metal ions that is very tightly bound to enzyme protein is called prosthetic group.
Reason: A complete, catalytically active enzyme together with its bound prosthetic group is called apoenzyme.

 2573  221 AIIMSAIIMS 2007 Report Error

Solution:

The term enzyme was coined by Kuhne in 1878. Enzymes may be simple of conjugated. Conjugated enzymes are made up of two parts ie, Apoenzymes (protein part of an enzyme) and cofactor (non protein part of an enzyme). When cofactor is an organic molecule and loosely attached with protein part, it is called Coenzyme.