Q. Amine that cannot be prepared by Gabriel- phthalimide synthesis is
Solution:
Only aliphatic primary amines can be prepared by Gabriel synthesis. Aniline cannot be prepared by this method because aryl halides ( or ) do not undergo nucleophilic substitution with potassium phthalimide under ordinary conditions to give N-phenyl phthalimide (ie, cleavage of bond in haloarenes is quite difficult)
( aliphatic halide)
