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AIPMTAIPMT 2015Principles of Inheritance and Variation
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The ability of a gene to have multiple phenotypic effects because it influences a number of characters simultaneously is known as pleiotropy. The gene having a multiple phenotypic effect because of its ability to control expression of two or more characters is called pleiotropic gene. In human beings pleiotropy is exhibited by syndromes called sickle cell anaemia and phenylketonuria.